Lyme Disease and Pregnancy
Author Information
Author(s): James M. Alexander, Susan M. Cox
Primary Institution: University of Texas Southwestern Medical Center
Hypothesis
What are the effects of Lyme disease on pregnancy and fetal outcomes?
Conclusion
Lyme disease can be transmitted to the fetus, but the actual risk of adverse fetal outcomes remains unclear.
Supporting Evidence
- Cases of transplacental passage of B. burgdorferi have been documented.
- A retrospective review revealed 5 infants with adverse fetal outcomes, but none appeared related to Lyme disease.
- Large surveys have shown a low prevalence of seropositivity in women at risk.
Takeaway
Lyme disease can pass from a mother to her baby during pregnancy, but we don't know how often this happens or if it causes problems for the baby.
Methodology
This review discusses the diagnosis, clinical course, and treatment of Lyme disease with an emphasis on the pregnant patient.
Limitations
The incidence of transplacental passage of Lyme disease and the actual risk of neonatal morbidity and mortality are currently unknown.
Participant Demographics
Women diagnosed with Lyme disease during pregnancy.
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