Effect of Dai-Kenchu-To on Postoperative Bowel Obstruction
Author Information
Author(s): Yasunaga Hideo, Miyata Hiroaki, Horiguchi Hiromasa, Kuwabara Kazuaki, Hashimoto Hideki, Matsuda Shinya
Primary Institution: The University of Tokyo
Hypothesis
Transluminally administered Dai-kenchu-to is effective for reducing a secondary operation for removal of intra-abdominal adhesion, duration of long-tube decompression, length of stay, and hospital charges.
Conclusion
Dai-kenchu-to is effective for reducing the duration of long-tube decompression and saving costs for patients with adhesive small bowel obstruction after colorectal cancer surgery.
Supporting Evidence
- Dai-kenchu-to users had a shorter duration of long-tube decompression compared to nonusers.
- Total hospital charges were significantly lower for Dai-kenchu-to users.
- The success rate of long-tube decompression was higher in Dai-kenchu-to users, but not statistically significant.
Takeaway
This study found that a Japanese herbal medicine called Dai-kenchu-to can help patients recover faster and spend less money when they have a blockage in their intestines after surgery.
Methodology
A retrospective observational study using a Japanese diagnosis procedure combination inpatient database with propensity score matching.
Potential Biases
Potential biases due to the nonrandomized nature of the study and missing data on confounding factors.
Limitations
The study was based on a nonrandomized, retrospective design and lacked data on obesity, cancer stage, or past history of laparotomies.
Participant Demographics
Patients who underwent colorectal cancer surgery with early postoperative adhesive small bowel obstruction.
Statistical Information
P-Value
0.012
Confidence Interval
95% CI, 1.08–1.84
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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