Blood groups and lung cancer
1988

Blood Groups and Lung Cancer

Sample size: 86 publication Evidence: moderate

Author Information

Author(s): T.E. Roberts, P. Hasleton, R. Swindell, R. Lawson

Primary Institution: University Hospital of South Manchester

Hypothesis

Is there an association between blood groups and survival in lung cancer patients?

Conclusion

Patients with blood group B or AB have shorter survival after lung cancer surgery compared to those with other blood groups.

Supporting Evidence

  • Patients with blood group B had a median survival of 24 months.
  • Patients with blood group AB had a median survival of 14 months.
  • Patients with blood group A had a median survival greater than 48 months.
  • Patients with blood group O had a median survival greater than 60 months.

Takeaway

This study found that people with certain blood types might not live as long after lung cancer surgery.

Methodology

The study analyzed survival rates of lung cancer patients based on their blood groups after surgery.

Potential Biases

Patients were a highly selected group, all operated on by one surgeon.

Limitations

The study had a small sample size for detailed analysis of histological types within each blood group.

Participant Demographics

Patients included 62 with squamous cell carcinomas, 20 with adenocarcinomas, and 4 with small cell carcinomas.

Statistical Information

P-Value

0.0017

Statistical Significance

p=0.0017

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