Vitamin A deficiency during pregnancy of HIV infected and non-infected women in tropical settings of Northwest Ethiopia
2011

Vitamin A Deficiency in Pregnant Women in Ethiopia

Sample size: 478 publication 10 minutes Evidence: moderate

Author Information

Author(s): Mulu Andargachew, Kassu Afework, Huruy Kahsay, Tegene Birhanemeskel, Yitayaw Gashaw, Nakamori Masayo, Van Nhien Nguyen, Bekele Assegedech, Wondimhun Yared, Yamamoto Shigeru, Ota Fusao

Primary Institution: University of Gondar

Hypothesis

What is the level of serum vitamin A and vitamin A deficiency among pregnant women with and without HIV infection in Northwest Ethiopia?

Conclusion

Vitamin A deficiency is a significant public health issue among pregnant women in Northwest Ethiopia, regardless of HIV status.

Supporting Evidence

  • 18.4% of pregnant women were found to be vitamin A deficient.
  • HIV positive pregnant women had significantly lower serum vitamin A levels compared to HIV negative pregnant women.
  • 46.7% of non-pregnant women with HIV infection were vitamin A deficient.

Takeaway

Many pregnant women in Ethiopia don't have enough vitamin A, which is important for their health and their babies' health.

Methodology

This cross-sectional study collected blood samples from 423 pregnant women and 55 healthy volunteers to measure serum vitamin A levels using high performance liquid chromatography.

Potential Biases

Potential bias due to the lack of control for acute phase responses and the small sample size of the control group.

Limitations

The study's findings may be influenced by the lack of precise reference values for vitamin A deficiency and the absence of measurements for acute phase response markers.

Participant Demographics

The mean age of pregnant women was 25.38 years, with 10.4% being HIV positive.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2458-11-569

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication