A computer-controlled potentiometric/spectrophotometric titrator
1988

Computer-Controlled Potentiometric/Spectrophotometric Titrator

Sample size: 3 publication Evidence: moderate

Author Information

Author(s): John D. Stong

Primary Institution: Merck Sharp & Dohme Research Laboratories

Conclusion

The study presents a reliable and efficient method for performing potentiometric and spectrophotometric titrations using a computer-controlled system.

Supporting Evidence

  • Replicate potentiometric titrations of glycines showed a relative standard deviation in titre of 1.035%.
  • Replicate spectrophotometric titrations of bromophenol blue yielded a pKa of 3.898 ± 0.075.
  • The system allows for machine-readable data, enhancing data manipulation and analysis.

Takeaway

This study shows how a computer can help scientists measure things more accurately and quickly when mixing liquids.

Methodology

The study describes the construction and operation of a computer-controlled titrator that integrates potentiometric and spectrophotometric techniques.

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