Psychological Status and Clinical Outcomes in Patients with Inflammatory Bowel Disease
Author Information
Author(s): Mikocka-Walus Antonina A, Turnbull Deborah A, Moulding Nicole T, Wilson Ian G, Holtmann Gerald J, Andrews Jane M
Primary Institution: University of Adelaide
Hypothesis
Patients with psychological co-morbidities are less likely to have better clinical outcomes (remission) at 12 months.
Conclusion
This study suggests that there is no temporal relationship between psychological problems at baseline and clinical outcomes over time.
Supporting Evidence
- Patients with inactive disease at baseline were at lower risk of relapse after 12 months.
- No significant relationship was found between psychological problems and the total number of relapses in the IBD group.
- Older participants were at greater risk of relapse after 12 months.
Takeaway
The study looked at whether being sad or anxious affects how well people with gut diseases get better, and it found that it doesn't seem to matter.
Methodology
An observational cohort prospective study with psychological and physical measures taken at baseline and after 12 months.
Potential Biases
Potential biases due to the observational nature of the study and the lack of control groups.
Limitations
The study was underpowered for the HCV and IBS groups, and the follow-up period may have been too short to observe significant relationships.
Participant Demographics
77 (62%) female and 47 (38%) male participants, mean age 50 years.
Statistical Information
P-Value
<0.001
Confidence Interval
0.012–0.178
Statistical Significance
p > 0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website