AD BLOOD BIOMARKERS IN DIVERSE COMMUNITY SETTINGS: A LONGITUDINAL PERSPECTIVE FROM THE ARIC STUDY
2024
Blood Biomarkers in Alzheimer's Disease and Related Dementias
Sample size: 1800
publication
Author Information
Author(s): Palta Priya, Sullivan Kevin, Merten Natascha
Primary Institution: Oxford University Press US
Hypothesis
Identifying individuals at risk for cognitive and physical decline during preclinical stages is essential for effective interventions.
Conclusion
The study presents findings on changes in blood biomarkers related to Alzheimer's disease and their associations with cognitive and mobility outcomes.
Supporting Evidence
- The study utilized 23 years of data from the ARIC Study.
- Blood biomarkers were assayed using Quanterix Simoa assays.
- Findings include associations of blood biomarkers with cognitive and mobility impairment.
Takeaway
Researchers are looking at blood tests to help find people at risk for Alzheimer's before they show symptoms, which could help in treating them earlier.
Methodology
The study analyzed blood biomarkers in ~1,800 participants from the ARIC Study at up to 3 timepoints.
Participant Demographics
Diverse community-based cohorts from the ARIC Study.
Digital Object Identifier (DOI)
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