SuiteMSA: Tools for Comparing Multiple Sequence Alignments
Author Information
Author(s): Anderson Catherine L, Strope Cory L, Moriyama Etsuko N
Primary Institution: University of Nebraska, Lincoln, Nebraska, USA
Conclusion
SuiteMSA provides researchers with tools to easily access sequence evolution simulations and evaluate the performance of multiple sequence alignment programs.
Supporting Evidence
- SuiteMSA allows users to visually compare multiple MSAs and identify areas of agreement and disagreement.
- The application includes a graphical user interface for a sequence evolution simulator that can generate reference MSAs.
- SuiteMSA provides alignment statistics to assist in the evaluation of MSA methods.
Takeaway
SuiteMSA is a software that helps scientists compare different ways of aligning DNA or protein sequences and also simulates how these sequences might evolve over time.
Methodology
SuiteMSA is a java-based application that provides unique MSA viewers and a sequence evolution simulator, allowing users to compare multiple MSAs and evaluate their consistency.
Limitations
The effectiveness of MSA methods can vary, and the simulation results depend on the evolutionary models used.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website