Association between the month of diagnosis and prognosis in breast carcinoma
1991

Month of Diagnosis and Breast Cancer Prognosis

Sample size: 738 publication Evidence: moderate

Author Information

Author(s): H. Joensuu, S. Toikkanen

Primary Institution: Turku University Central Hospital

Hypothesis

Does the month of diagnosis affect the prognosis of breast cancer?

Conclusion

Breast cancer diagnosed in certain months has a poorer prognosis compared to others.

Supporting Evidence

  • Mortality in breast cancer was greater if diagnosed in January, February, or August to October in 1945-65.
  • Survival was significantly inferior among both premenopausal and postmenopausal women diagnosed in July to September in 1980-84.
  • Cancers diagnosed during unfavourable months had more extensive tumour necrosis and larger primary tumour size.

Takeaway

When women find out they have breast cancer in certain months, they might not do as well as those diagnosed in other months.

Methodology

The study analyzed survival rates of breast cancer patients diagnosed in different months over two time periods.

Potential Biases

Potential biases in patient follow-up and diagnosis timing.

Limitations

The study may not account for all confounding factors affecting prognosis.

Participant Demographics

Female patients with unilateral invasive breast cancer from Turku, Finland.

Statistical Information

P-Value

0.009

Statistical Significance

p<0.05

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