Comparative Analysis of Fatty Acid Bioaccessibility in Commercial Marine Oil Supplements: An In Vitro Integrated Analytical Study
2024

Comparative Analysis of Fatty Acid Bioaccessibility in Marine Oil Supplements

publication Evidence: moderate

Author Information

Author(s): Montebugnoli Thomas, Antonelli Giorgia, Babini Elena, Vasini Ester Maria, Danesi Francesca, Jónasdóttir Sigrún Huld, Gudjónsdóttir María, Capozzi Francesco, Bordoni Alessandra

Primary Institution: Department of Agricultural and Food Sciences (DISTAL), University of Bologna, Italy

Hypothesis

The study aims to evaluate how the release of fatty acids from marine oils during digestion is influenced by their esterification form and encapsulation.

Conclusion

The source of marine oil and its encapsulation significantly impact the bioaccessibility of fatty acids, which likely modulates their effectiveness.

Supporting Evidence

  • The release of free fatty acids after simulated digestion mainly depends on the oil source.
  • Calanus oils showed the lowest free fatty acid release due to high amounts of wax esters.
  • Encapsulation can modulate the absorption and blood concentration of n-3 LC-PUFAs.
  • Different lipid classes in oils influence their bioaccessibility during digestion.

Takeaway

This study looks at how well our bodies can absorb fatty acids from different types of fish oil supplements, showing that some oils are easier to digest than others.

Methodology

The study used in vitro digestion methods and two analytical techniques, TLC-FID and 1H-NMR spectroscopy, to evaluate fatty acid release from different marine oil supplements.

Limitations

The study did not include gastric lipase in the digestion protocol, which may affect the bioaccessibility results.

Statistical Information

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/foods13244177

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