Energy Expenditure During Overfeeding
Author Information
Author(s): Annemiek MCP Joosen, Klaas R Westerterp
Primary Institution: Maastricht University
Hypothesis
Can adaptive thermogenesis be identified in overfeeding experiments?
Conclusion
Evidence for adaptive thermogenesis in humans during overfeeding is inconsistent and often attributed to measurement errors and individual variations.
Supporting Evidence
- Some studies found evidence for adaptive thermogenesis based on smaller than expected weight gains.
- Other studies showed weight gains proportional to the amount of overfeeding, suggesting no adaptive thermogenesis.
- Measurement errors and individual differences may obscure the presence of adaptive thermogenesis.
Takeaway
When people eat more than they need, they don't always gain as much weight as expected, and scientists are trying to figure out why some people can burn off extra energy better than others.
Methodology
The study reviewed 16 human overfeeding experiments to assess energy expenditure and weight gain.
Potential Biases
Potential biases due to differences in study protocols and participant demographics.
Limitations
Variability in individual responses and measurement errors complicate the assessment of adaptive thermogenesis.
Participant Demographics
Healthy adult subjects, with a mix of normal weight and overweight individuals.
Digital Object Identifier (DOI)
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