Apoptosis is induced in both drug-sensitive and multidrug-resistant hepatoma cells by somatostatin analogue TT-232
1999
Somatostatin Analogue TT-232 Induces Apoptosis in Liver Cancer Cells
publication
Author Information
Author(s): Diaconu C-C, Szathmári M, Kéri G, Venetianer A
Primary Institution: Institute of Genetics, Biological Research Center, Hungarian Academy of Sciences
Hypothesis
TT-232 can induce apoptosis in both drug-sensitive and multidrug-resistant hepatoma cells.
Conclusion
TT-232 effectively induces apoptosis in various hepatoma cell lines, regardless of their drug resistance.
Supporting Evidence
- TT-232 has a strong antiproliferative effect on hepatocellular carcinoma cell lines.
- The drug induces apoptosis in both drug-sensitive and multidrug-resistant cells.
Takeaway
A special medicine called TT-232 can make cancer cells in the liver die, even if they usually resist treatment.
Digital Object Identifier (DOI)
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