Phylogenetic inferences reveal multiple intra- and interhost genetic diversity among bat rabies viruses circulating in northeastern Brazil
2025

Genetic Diversity of Bat Rabies Viruses in Northeastern Brazil

Sample size: 356 publication 10 minutes Evidence: moderate

Author Information

Author(s): de Sousa Larissa Leão F., Guilardi Mariana Dias, Martins Junior Olimpio, Alves Bruna Stefanie S., Tibo Luiz Henrique S., da Silva-Antunes Patrícia, Cabral-Miranda Gustavo, Caldeira Débora Bellini, Brandão Paulo Eduardo, Campos Fabrício Souza, Janini Luiz Mário R., Durães-Carvalho Ricardo

Primary Institution: Federal University of São Paulo, São Paulo, SP Brazil

Hypothesis

What is the genetic diversity of rabies viruses circulating among bats in northeastern Brazil?

Conclusion

The study reveals significant genetic diversity of rabies viruses among different bat species in northeastern Brazil.

Supporting Evidence

  • 12.07% of the samples tested positive for rabies using direct immunofluorescence.
  • 40 samples were confirmed positive by both direct immunofluorescence and mouse inoculation tests.
  • Phylogenetic analysis revealed three distinct clusters of rabies viruses.

Takeaway

Scientists studied bats in Brazil to see how different types of rabies viruses spread among them. They found many different kinds of the virus.

Methodology

The study involved collecting 356 bat brain samples and testing them for rabies using various diagnostic techniques.

Limitations

The sample size may not fully represent the entire bat population, and the focus on deceased specimens may overlook the full spectrum of rabies diversity.

Participant Demographics

Samples were collected from 20 different bat species in the State of Ceará, Brazil.

Digital Object Identifier (DOI)

10.1186/s42522-024-00124-6

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