Intrauterine Infection and Preterm Labor
1995
Intrauterine Infection and Preterm Labor
Sample size: 15
publication
Evidence: moderate
Author Information
Author(s): Manju Monga, Jorge D. Blanco
Primary Institution: University of Texas Medical School at Houston
Hypothesis
Intrauterine infection plays an important role in the pathogenesis of preterm labor.
Conclusion
Intrauterine infection may significantly contribute to the onset of preterm labor and delivery.
Supporting Evidence
- 12.2% of women in preterm labor with intact membranes had microbial invasion of the amniotic cavity.
- Women with positive cultures were more likely to develop clinical chorioamnionitis.
- 81 of 160 women with negative cultures subsequently developed preterm labor.
Takeaway
Sometimes, infections inside the womb can make babies come out too early, which can be dangerous.
Methodology
The article reviews clinical data and studies related to intrauterine infection and preterm labor.
Limitations
The article does not provide specific limitations of the studies reviewed.
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