Global Variation of Nasopharynx Cancer
Author Information
Author(s): Sun Xin, Tong Li-Ping, Wang Yu-Tong, Wu Yong-Xiang, Sheng Hong-Shen, Lu Lian-Jun, Wang Wen
Primary Institution: Fourth Military Medical University, Xi'an, Shaanxi Province, People's Republic of China
Hypothesis
Can global variation of nasopharynx cancer be retrieved from combined analyses of IARC cancer information databases?
Conclusion
NPC mortality rate is about 2–3 times higher in males than in females and shows a decreasing tendency in selected countries/regions.
Supporting Evidence
- NPC incidence rates are significantly higher in South-Eastern Asia, Micronesia, and Southern Africa.
- The highest NPC mortality rates were found in regions like Hong Kong, Singapore, and Malta.
- The study highlights the need for improved cancer registry systems in high incidence areas.
Takeaway
This study looks at how nasopharyngeal cancer rates differ around the world and finds that men are more affected than women, with rates dropping in some areas.
Methodology
The study analyzed NPC epidemiological data from GLOBOCAN2008 and WHO mortality databases using Joinpoint analysis.
Potential Biases
Potential bias due to incomplete cancer entries in high incidence regions.
Limitations
The study's findings are limited by the quality and completeness of cancer registry data in various regions.
Participant Demographics
The study focuses on global populations with specific emphasis on regions with high NPC incidence.
Statistical Information
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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