Royal Jelly Helps Improve Memory in Mice
Author Information
Author(s): Hattori Noriko, Ohta Shozo, Sakamoto Takashi, Mishima Satoshi, Furukawa Shoei
Primary Institution: Nagaragawa Research Center, API Co., Ltd
Hypothesis
Does royal jelly stimulate the regeneration of neurons in the hippocampus and improve cognitive function in mice intoxicated with trimethyltin?
Conclusion
Royal jelly significantly increased the number of neurons in the hippocampus and improved cognitive impairment in trimethyltin-intoxicated mice.
Supporting Evidence
- Royal jelly increased the number of granule cells in the hippocampus.
- Feeding mice with royal jelly improved their performance in memory tests.
- Trimethyltin treatment caused significant neuronal loss in the hippocampus.
Takeaway
Royal jelly, a substance made by bees, can help mice think better after they've been poisoned.
Methodology
Male ICR mice were treated with trimethyltin and fed diets containing different concentrations of royal jelly, followed by behavioral tests and neuronal counting.
Potential Biases
Potential bias in the selection of animal models and the specific strains used.
Limitations
The study was conducted only on male mice, which may limit the generalizability of the findings.
Participant Demographics
Male ICR mice, 7 weeks old.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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