Cromoglycate and nedocromil influence on airway reactivity
1994
Cromoglycate and Nedocromil's Influence on Airway Reactivity
publication
Evidence: moderate
Author Information
Author(s): E. A. Valletta, A. L. Boner
Primary Institution: University of Verona
Hypothesis
The inflammatory process in asthma is key to modulating bronchial hyper-responsiveness (BHR).
Conclusion
Sodium cromoglycate and nedocromil sodium are effective in reducing bronchial hyper-responsiveness in asthma patients.
Supporting Evidence
- Sodium cromoglycate and nedocromil sodium have demonstrated good anti-inflammatory activity.
- Both drugs offer protection against various inhalation challenges.
- Long-term use of these drugs is advisable for managing mild-to-moderate asthma.
Takeaway
This study shows that certain medicines can help kids with asthma breathe better by reducing how sensitive their airways are.
Methodology
The study reviews existing literature on the effects of sodium cromoglycate and nedocromil sodium on bronchial hyper-responsiveness.
Limitations
The basic mechanisms of action of sodium cromoglycate and nedocromil sodium are not completely understood.
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