Acute lung injury and the acute respiratory distress syndrome in Ireland: a prospective audit of epidemiology and management
2008

Acute Lung Injury and ARDS in Ireland: A Study

Sample size: 1029 publication Evidence: moderate

Author Information

Author(s): The Irish Critical Care Trials Group

Primary Institution: Royal Victoria Hospital

Hypothesis

What is the epidemiology and management of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) in Ireland?

Conclusion

The incidence of ALI/ARDS is high and is associated with significant mortality.

Supporting Evidence

  • 19% of ICU admissions had ALI/ARDS.
  • The overall ICU mortality for ALI/ARDS was 32.3%.
  • Patients receiving statins had a trend towards lower mortality.

Takeaway

Many people in Ireland get very sick from lung problems, and a lot of them need special breathing help. This study helps us understand how to take care of them better.

Methodology

A 10-week prospective national audit was conducted across 14 ICUs in Ireland to identify patients with ALI/ARDS.

Potential Biases

Misclassification of ALI/ARDS may occur due to interpretation of chest radiographs.

Limitations

Data on co-morbidities were not collected, and height was not recorded to calculate predicted body weight accurately.

Participant Demographics

Mean age was 58 years, with 62% male.

Statistical Information

P-Value

0.09

Confidence Interval

0.06 to 1.21

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/cc6808

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