The confused cancer patient: a case of 5-fluorouracil–induced encephalopathy
2008

Case of 5-Fluorouracil-Induced Encephalopathy

Sample size: 1 publication Evidence: low

Author Information

Author(s): Cheung W.Y. MD, Fralick R.A. MD, Cheng S. MD

Primary Institution: University of Toronto

Conclusion

The patient recovered from 5-fluorouracil-induced encephalopathy after treatment with lactulose and discontinuation of the drug.

Supporting Evidence

  • The patient experienced seizures and confusion after receiving 5-fluorouracil chemotherapy.
  • Elevated ammonia levels were noted in the patient.
  • The patient improved after stopping 5-fluorouracil and receiving lactulose.

Takeaway

A man developed confusion and seizures after chemotherapy, but he got better after stopping the medicine and taking a special syrup.

Methodology

Case report detailing the patient's symptoms, treatment, and recovery.

Limitations

The findings are based on a single case, limiting generalizability.

Participant Demographics

53-year-old Korean man with stage III colon cancer.

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