Sexual Behaviour and HPV Infections in 18 to 29 Year Old Women in the Pre-Vaccine Era in the Netherlands
2008

HPV Infections and Sexual Behavior in Young Women

Sample size: 2065 publication 10 minutes Evidence: moderate

Author Information

Author(s): Charlotte H. Lenselink, Willem J. G. Melchers, Wim G. V. Quint, Annelies M. J. Hoebers, Jan C. M. Hendriks, Leon F. A. G. Massuger, Ruud L. M. Bekkers

Primary Institution: Radboud University Nijmegen Medical Centre

Hypothesis

What are the prevalence and risk factors for HPV infections among unscreened women aged 18 to 29 in the Netherlands?

Conclusion

The study found that sexual behavior, particularly the number of sexual partners, is a significant predictor of HPV prevalence among young women.

Supporting Evidence

  • HPV point prevalence in the sample was 19%.
  • Low risk HPV prevalence was 9.1% and high risk HPV prevalence was 11.8%.
  • Number of lifetime sexual partners was the most powerful predictor of HPV positivity.
  • HPV types 16 and 18 were found in only 0.1% of the women.

Takeaway

This study looked at young women in the Netherlands to see how many had HPV and what factors made them more likely to have it. They found that having more sexual partners increased the chances of having HPV.

Methodology

A cross-sectional study where women self-collected cervico-vaginal samples and completed a questionnaire about their sexual behavior.

Potential Biases

Potential bias due to self-reported data on sexual behavior.

Limitations

The study may not be generalizable due to the overrepresentation of women attending university.

Participant Demographics

Women aged 18 to 29, predominantly Dutch ethnicity, with a significant portion attending higher education.

Statistical Information

P-Value

p<0.001

Confidence Interval

95% CI overlapping with adjacent age groups considered accidental findings.

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0003743

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