Ondansetron and Severe Bradycardia in a Renal Transplant Patient
Author Information
Author(s): Sandeep Sahu, Sunaina Tejpal Agarwal, Anil Ambesh, Sushil Prakash Srivastava, Aneesh
Primary Institution: Sanjay Gandhi Post Graduate Institute of Medical Sciences
Hypothesis
Can ondansetron cause severe cardiovascular events in patients with chronic kidney disease?
Conclusion
Ondansetron can lead to severe bradycardia and hypotension in patients with complex medical histories, such as chronic kidney disease.
Supporting Evidence
- Ondansetron is known to cause adverse cardiovascular events.
- The patient experienced a significant drop in heart rate and blood pressure after ondansetron administration.
- Bradycardia and hypotension were resolved with atropine and monitoring.
- Chronic kidney disease and multiple medications may influence the response to ondansetron.
Takeaway
A patient had a dangerous drop in heart rate after receiving ondansetron during a kidney transplant, showing that this medicine can have serious side effects.
Methodology
Case report of a renal transplant patient who experienced severe bradycardia and hypotension after ondansetron administration.
Limitations
The case is based on a single patient, limiting generalizability.
Participant Demographics
A 27-year-old female with chronic kidney disease and hypertension.
Digital Object Identifier (DOI)
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