Case Report of an Adolescent with Wegener's Granulomatosis and Blastomycosis
Author Information
Author(s): Reem Abdwani, Kristin Houghton, Simon Dobson, Maureen O'Sullivan, Peter Malleson
Primary Institution: Sultan Qaboos University Hospital, Muscat, Oman
Hypothesis
Blastomycosis infection may trigger systemic granulomatous vasculitis in predisposed individuals.
Conclusion
This case suggests a possible link between blastomycosis and Wegener's Granulomatosis, warranting further investigation.
Supporting Evidence
- This is the first reported case of Wegener's Granulomatosis co-existing with blastomycosis.
- The patient had a positive C-ANCA test, indicating a diagnosis of Wegener's Granulomatosis.
- Blastomycosis is endemic in regions like Kenora, Ontario, where the patient had traveled.
Takeaway
A girl got very sick from two diseases at the same time: one that affects her blood vessels and another from a fungus. Doctors think the fungus might have caused the blood vessel disease.
Methodology
The case was diagnosed through clinical presentation, imaging, and biopsy.
Limitations
The study is based on a single case report, limiting generalizability.
Participant Demographics
A 16-year-old previously healthy girl.
Digital Object Identifier (DOI)
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