Ferulic Acid Relieves the Oxidative Stress Induced by Oxidized Fish Oil in Oriental River Prawn (Macrobrachium nipponense) with an Emphasis on Lipid Metabolism and Gut Microbiota
2024

Ferulic Acid Helps Prawns Fight Stress from Bad Fish Oil

Sample size: 360 publication 10 minutes Evidence: high

Author Information

Author(s): Liu Xin, Sun Cunxin, Zhou Qunlan, Zheng Xiaochuan, Jiang Sufei, Wang Aimin, Han Yongquan, Xu Gangchun, Liu Bo, Rufián-Henares José Ángel

Primary Institution: Nanjing Agricultural University

Hypothesis

Can ferulic acid reduce the negative effects of oxidized fish oil on the growth and health of Macrobrachium nipponense?

Conclusion

Ferulic acid supplementation can alleviate oxidative stress and improve lipid metabolism in prawns affected by oxidized fish oil.

Supporting Evidence

  • Oxidized fish oil significantly reduced growth performance and increased lipid accumulation in prawns.
  • Ferulic acid supplementation improved the expression of antioxidant genes.
  • Ferulic acid reduced the diversity of gut microbiota affected by oxidized fish oil.
  • Supplementation with ferulic acid increased total bile acids in the prawns.

Takeaway

This study found that adding ferulic acid to the diet of prawns helps them stay healthy when they eat bad fish oil.

Methodology

Prawns were divided into four groups and fed different diets for 10 weeks, followed by growth and biochemical parameter assessments.

Potential Biases

Potential bias in the selection of dietary treatments and environmental conditions.

Limitations

The study was limited to a specific duration and only one species of prawn.

Participant Demographics

Oriental river prawn (Macrobrachium nipponense) with an initial weight of 0.140 ± 0.015 g.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/antiox13121463

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