The treatment of early breast cancer in women over the age of 70
Author Information
Author(s): Alistair Ring, Mark Reed, Richard Leonard, Isla Kunkler, H. Ballard Muss, H. Wildiers, L. Fallowfield, A. Jones, R. Coleman
Hypothesis
What represents optimal treatment for older women with early breast cancer?
Conclusion
Older women with breast cancer should be treated according to tumor biology, considering their co-morbidities and frailty.
Supporting Evidence
- One third of all breast cancers are diagnosed in women aged 70 or over.
- Older women are less likely to receive standard treatment for breast cancer.
- Primary surgery and endocrine therapy are discussed as treatment options.
- Adjuvant chemotherapy and radiotherapy are also considered for older patients.
- Older patients may have better quality of life outcomes than younger patients after certain treatments.
Takeaway
This study looks at how to treat breast cancer in older women, who often don't get the same treatments as younger women. It suggests that doctors should consider each woman's health and preferences when deciding on treatment.
Methodology
This minireview summarizes existing evidence and ongoing clinical trials regarding the management of early breast cancer in women aged 70 and over.
Potential Biases
The review may be biased due to the lack of representation of older women in clinical trials.
Limitations
Older women are under-represented in clinical trials, leading to uncertainty in optimal treatment.
Participant Demographics
The focus is on women aged 70 and over with early breast cancer.
Digital Object Identifier (DOI)
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