In-hospital cerebrovascular complications following orthotopic liver transplantation: A retrospective study
2008

Cerebrovascular Complications After Liver Transplantation

Sample size: 337 publication Evidence: moderate

Author Information

Author(s): Ling Li, He Xiaoshun, Zeng Jinsheng, Liang Zhijian

Primary Institution: First Affiliated Hospital, Sun Yat-Sen University

Hypothesis

What are the clinical features and risk factors for cerebrovascular complications following orthotopic liver transplantation?

Conclusion

Cerebrovascular complications significantly impact the outcomes of patients who undergo liver transplantation, with older age and systemic infection being potential risk factors.

Supporting Evidence

  • 3.0% of patients developed in-hospital cerebrovascular complications.
  • Older age and systemic infection were associated with higher rates of intracranial hemorrhage.
  • Six out of ten patients with cerebrovascular complications died.

Takeaway

After liver transplant, some patients can have serious brain problems, especially if they are older or have infections.

Methodology

The study reviewed 337 patients who underwent 358 liver transplants, analyzing clinical and neuroimaging features of cerebrovascular complications.

Potential Biases

Potential biases may arise from the retrospective nature of the study and the specific patient population.

Limitations

The study is retrospective and may not capture all relevant data on complications.

Participant Demographics

Mean age was 47 years, with 288 males and 49 females.

Statistical Information

P-Value

0.011

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2377-8-52

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