Br. J. Cancer (1988). 57, 219-232
1988

Growth Factors and Their Role in Cancer

publication Evidence: moderate

Author Information

Author(s): C.-H. Heldin, A. Hammacher, A. Ostman, C. Betsholtz, B. Westermark, H.L. Moses, A.B. Roberts, M.B. Sporn, E. Rozengurt, I. Zachary, J. Sinnett-Smith, E. Nanberg, P.J. Woll, J. Millar, R. Ross, C.S. Henney, T.M. Dexter, B.L. Vallee, M.D. Waterfield, D.M. Barnes, G.A. Lammie, W.L. Gullick, R.R. Millis, D.G. Godfrey, C. Porteous, W.D. George, I. Pragnell, S. Cowan, R.E. Leake, F.G. Hay, R. Milroy, L.W. Adams, S.G. Allan, M.R. Adamson, R.C.F. Leonard, H.D. Dazzi, P.S. Hasleton, T.E. Roberts, N. Thatcher, K.S. Tonkin, M. Berger, M. Ormerod, L.R. Kelland, P. Haralabos, C.G. McKenzie, D. Thomas, A.G. Epenetos, M. Shearer, J. Taylor-Papadimitriou, M. Partridge, M. Green, P.J. Barrett-Lee, M.T. Travers, Y.A. Luqmani, R.C. Coombes, S. Farmer, D.B. Jones, D. Davies, P. Alexander, J. Blackler, P. Alexander, S. Farmer, D. Davies, J.W. Sweetenham, D. Davies, J. Blackler, P. Alexander, D. Wynford-Thomas, D.W. Williams, E.D. Williams, T.D. France, M.E.A. Phillips, C.L. Eaton, P. Davies, N.T. Goode, I.R. Hart, P.D. Webb, P. Kenton, A.R. Mire-Sluis, A.V. Hoffbrand, R.G. Wickremasinghe, P.R. Tempest, C.S. Cooper, R.E. Wilson, T. Dooley, I.R. Hart, S.A. Watson, L.G. Durrant, D.L. Morris, J.G. Reeve, J.J. Shaw, N.M. Bleehen, P.J. Woll, E. Rozengurt, T.-P.D. Fan, S.P. Andrade, J. Saklatvala, A.L. Jones, B.C. Millar, J.G.B. Bell, J.L. Millar, S. Devereux, D. Campos Costa, J. Gribben, M.F. Spittle, A.M. Jelliffe, A.H. Goldstone, D.C. Linch, M. Hernandez Bronchud, T.M. Dexter, N. Thatcher, J.H. Scarffe, F. Balkwill, R. Osborne, F. Burke, S. Naylor, D. Talbot, H. Durbin, W. Fiers

Hypothesis

The study investigates the involvement of various growth factors in cancer cell proliferation and their potential roles in tumorigenesis.

Conclusion

The findings suggest that different growth factors have distinct roles in cell growth and may contribute to cancer development.

Takeaway

This study looks at how certain proteins help cells grow and how they might be involved in cancer.

Methodology

The study involved various experiments examining the effects of growth factors on different cell lines and tissues.

Limitations

The study does not specify the limitations of the research.

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