Oral Microbiome Changes in Children After Dental Treatment
Author Information
Author(s): Zahirrah Rasheed, Sheng Chew Wei, Norfitriah Erika, Nasruddin Nurrul Shaqinah, Yazid Farinawati
Primary Institution: Universiti Kebangsaan Malaysia
Hypothesis
How does dental treatment affect the oral microbiome in children with varying levels of caries?
Conclusion
Dental treatment increases oral microbiome diversity in children, but some harmful bacteria may persist, indicating a need for ongoing oral health education.
Supporting Evidence
- Most children with caries were between seven and eight years of age.
- 61% of participants came from middle-income families.
- Post-treatment, there was a significant increase in alpha-diversity of the oral microbiome.
Takeaway
This study shows that after kids get their teeth treated, the types of bacteria in their mouths change for the better, but some bad bacteria can still stick around.
Methodology
Saliva samples were collected from children with different caries statuses before and after dental treatment, and analyzed using 16S rRNA gene sequencing.
Potential Biases
Potential biases due to the small sample size and limited dietary information.
Limitations
The study had a small sample size for each caries group and a short follow-up period of three months after treatment.
Participant Demographics
Children aged 7 to 12 years, predominantly from middle-income families, with a mix of genders.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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