Unusual cause of weight loss in a patient with HIV–hepatitis C virus coinfection
2010

Weight Loss Due to Interferon-Induced Thyroiditis in an HIV and Hepatitis C Patient

publication Evidence: low

Author Information

Author(s): Atul Gogia, A. Kakar

Primary Institution: Sir Ganga Ram Hospital, New Delhi, India

Hypothesis

Can interferon therapy for hepatitis C cause thyroid dysfunction leading to weight loss in patients with HIV coinfection?

Conclusion

Interferon-induced thyroid dysfunction is a rare side effect that can lead to significant weight loss, but it can be managed without discontinuing treatment.

Supporting Evidence

  • Interferon therapy can lead to autoimmune thyroiditis, which is a rare side effect.
  • The patient experienced significant weight loss due to interferon-induced thyroiditis.
  • Regular thyroid function tests are recommended during interferon therapy.

Takeaway

Sometimes, medicine can make you lose weight because it affects your thyroid, which helps control your body's energy. Doctors can help fix this with other medicines.

Methodology

Case report detailing the patient's medical history, treatment, and response to therapy.

Limitations

The findings are based on a single case report, limiting generalizability.

Participant Demographics

31-year-old male with HIV and hepatitis C coinfection.

Digital Object Identifier (DOI)

10.4103/2589-0557.75004

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