Markers Predicting Respiratory Issues in Premature Infants
Author Information
Author(s): Chen Xuexin, Li Yuedong, Chen Hongxiang, Chen Weiming
Primary Institution: Meizhou People’s Hospital, Meizhou Academy of Medical Sciences
Hypothesis
This study aims to investigate the association between immunoinflammatory markers and the risk of developing respiratory distress syndrome (RDS) in premature infants.
Conclusion
Adverse pregnancy history, placental abnormalities, low birth weight, elevated SIRI and NAR were associated with increased risk of RDS and secondary infections in premature infants.
Supporting Evidence
- 962 infants developed RDS, while 1202 did not.
- SII, SIRI, and NAR levels were significantly elevated in RDS infants.
- Adverse pregnancy history and low birth weight were significant predictors of RDS.
Takeaway
Doctors can use certain blood markers to help find out if premature babies might have breathing problems.
Methodology
This was a retrospective study analyzing clinical records of 2164 premature infants, comparing those with and without RDS using logistic regression.
Potential Biases
Potential bias due to the retrospective nature and single-center design.
Limitations
The study is retrospective, may have omitted influencing factors, and is based on a single center.
Participant Demographics
The study included 1237 male and 927 female premature infants.
Statistical Information
P-Value
p<0.001
Confidence Interval
95% CI for ORs provided in the results
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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