Predicting Catheter Ablation Outcomes for Atrial Fibrillation Using P-Wave Parameters
Author Information
Author(s): Antoun Ibrahim, Li Xin, Vali Zakariyya, Kotb Ahmed, Abdelrazik Ahmed, Koev Ivelin, Somani Riyaz, Ng G. André
Primary Institution: University Hospitals of Leicester NHS Trust
Hypothesis
This study aims to correlate P-wave parameters after pulmonary vein isolation (PVI) with outcomes.
Conclusion
Increased PWDc and PWA after PVI were independently associated with failed ablation for paroxysmal atrial fibrillation.
Supporting Evidence
- Increased PWDc and PWA were associated with failed ablation outcomes.
- Patients with failed PVI had increased PWDc after PVI compared to successful PVI.
- PWA increased significantly after both failed and successful PVI.
Takeaway
Doctors can look at certain heart wave patterns to see if a treatment for heart rhythm problems will work or not.
Methodology
This single-center retrospective study included consecutive patients with first-time PVI for PAF between 2018 and 2019, measuring P-wave parameters before and after ablation.
Potential Biases
Exclusion of patients on amiodarone and those with significant structural heart disease may limit applicability to broader populations.
Limitations
The study's retrospective nature limits causal inferences, and the single-center design may limit generalizability.
Participant Demographics
Males comprised 71% of the patients; the mean age was 60.
Statistical Information
P-Value
p<0.001
Confidence Interval
95% CI: 1.4–4.2
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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