Primitive Oocyte-like Cells in Ovarian Cancer
Author Information
Author(s): Irma Virant-Klun, Thomas Skutella, Branko Cvjeticanin, Martin Stimpfel, Jasna Sinkovec
Primary Institution: University Medical Centre Ljubljana, Slovenia
Hypothesis
Are primitive oocyte-like cells in the adult ovarian surface epithelium related to serous papillary adenocarcinoma?
Conclusion
Primitive oocyte-like cells in the adult ovarian surface epithelium may be linked to the development of serous papillary adenocarcinoma.
Supporting Evidence
- Primitive oocyte-like cells were found in the ovarian surface epithelium of a 67-year-old patient.
- These cells expressed markers associated with pluripotency.
- The presence of these cells is not typical in healthy adult ovaries.
Takeaway
This study found unusual cells in the ovaries of an older woman that might be connected to cancer. These cells are not usually found in healthy ovaries.
Methodology
Ovarian tissue was surgically retrieved and analyzed histologically and immunohistochemically for specific cell markers.
Limitations
The study is based on a single case, limiting the generalizability of the findings.
Participant Demographics
67-year-old female patient.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website