Psychometric validation of the revised SCOPA-Diary Card: expanding the measurement of non-motor symptoms in Parkinson's disease
2011

Revised SCOPA-Diary Card for Parkinson's Disease

Sample size: 101 publication Evidence: moderate

Author Information

Author(s): Rendas-Baum Regina, Buck Philip O, White Michelle K, Castelli-Haley Jane

Primary Institution: QualityMetric Inc.

Hypothesis

The factorial structure of the Revised SCOPA-DC would be best represented by a 2-factor structure, corresponding to motor and non-motor symptom domains.

Conclusion

The Revised SCOPA-DC is a valid and reliable instrument for measuring the impact of Parkinson's disease symptoms and the severity of off-time.

Supporting Evidence

  • The Revised SCOPA-DC included several format changes and the addition of non-motor symptoms based on patient input.
  • Confirmatory factor analysis indicated that the Revised SCOPA-DC was best represented by a three-factor structure.
  • Scores on the Revised SCOPA-DC were lower among patients who reported experiencing off-time compared to those without off-time.

Takeaway

This study created a new diary card to help people with Parkinson's disease track their symptoms better, especially the ones that aren't about movement.

Methodology

A convenience sample of 101 PD patients was surveyed using the Revised SCOPA-DC, which was developed based on focus group input and validated through confirmatory factor analysis.

Potential Biases

Potential bias from self-reported PD diagnosis and online recruitment methods.

Limitations

Online recruitment may have introduced bias, self-reported diagnosis could lead to misclassification, and a standardized scale of non-motor symptoms was not used.

Participant Demographics

Participants were mostly white (88.1%), male (50.5%), and had been diagnosed with PD for an average of 7.4 years.

Statistical Information

P-Value

p<0.05

Confidence Interval

(0.00, 0.10)

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1477-7525-9-69

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