Prediction of fluid responsiveness in septic shock patients: comparing automated pulse pressure variation by IntelliVue MP monitor and stroke volume variation by FloTracâ„¢/Vigileoâ„¢
2011

Predicting Fluid Responsiveness in Septic Shock Patients

Sample size: 42 publication Evidence: moderate

Author Information

Author(s): Khwannimit B, Bhurayanontachai R

Primary Institution: Songklanagarind Hospital, Songkhla, Thailand

Hypothesis

The study aims to assess and compare the ability of pulse pressure variation and stroke volume variation to predict fluid responsiveness in septic shock patients.

Conclusion

Both automated pulse pressure variation and stroke volume variation are effective in predicting fluid responsiveness in patients with septic shock.

Supporting Evidence

  • 27 out of 42 patients (64.3%) were classified as fluid responders.
  • PPV and SVV were significantly higher in responders than in nonresponders.
  • The baseline PPV correlated with the baseline SVV with a correlation coefficient of r = 0.96.

Takeaway

The study looked at how well two different methods can tell if patients with septic shock need more fluids, and found that both methods work well.

Methodology

A prospective study measuring SVV and PPV in 42 mechanically ventilated septic shock patients before and after fluid administration.

Participant Demographics

Mechanically ventilated septic shock patients.

Statistical Information

P-Value

P < 0.001

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1186/cc9473

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