Effects of Elective Percutaneous Coronary Intervention on Subtle Left Ventricular Systolic Dysfunction in Patients With Stable Coronary Artery Disease as Assessed by Global Longitudinal Strain Imaging
2024

Impact of Heart Procedure on Heart Function in Patients with Stable Heart Disease

Sample size: 94 publication Evidence: moderate

Author Information

Author(s): Muacevic Alexander, Adler John R, Venu Swargam, Iyer Ramnath Venkitasubramonia, Dash Prabath Kumar

Primary Institution: Sri Sathya Sai Institute of Higher Medical Sciences

Hypothesis

Can elective percutaneous coronary intervention improve subtle left ventricular systolic dysfunction in patients with stable coronary artery disease?

Conclusion

Elective percutaneous coronary intervention significantly improves subtle left ventricular dysfunction in patients with stable coronary artery disease.

Supporting Evidence

  • Patients showed significant improvement in global longitudinal strain at both 24 hours and six months post-PCI.
  • Baseline GLS was significantly correlated with the severity of coronary artery disease.
  • Patients with single-vessel disease had the highest proportion in the study.

Takeaway

Doctors found that a heart procedure can help patients with heart problems feel better, even if their heart function seemed normal before.

Methodology

This was a prospective, observational study involving 94 patients with stable coronary artery disease who underwent echocardiography and global longitudinal strain assessment before and after the procedure.

Limitations

The study had a small sample size and did not assess the impact of CABG on GLS.

Participant Demographics

The average age was 51.85 years, with 73.4% male, and common risk factors included dyslipidemia (62.8%) and hypertension (55.3%).

Statistical Information

P-Value

<0.001

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.7759/cureus.75133

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