A Case of Valproate Induced Hyperammonemic Encephalopathy
2011
Case of Valproate Induced Hyperammonemic Encephalopathy
Sample size: 1
publication
Evidence: low
Author Information
Author(s): Surjit Tarafdar, Slee Mark, Ameer Faisal, Doogue Matt
Primary Institution: Flinders Medical Centre
Conclusion
The patient recovered from valproate induced hyperammonemic encephalopathy after discontinuing the medication and normalizing serum ammonia levels.
Supporting Evidence
- Valproate induced hyperammonemic encephalopathy can occur even with normal liver function tests.
- Symptoms may include confusion, lethargy, and vomiting.
- Discontinuation of valproate and supportive care are effective treatments.
Takeaway
A man got very confused because of a medicine he was taking, but he got better after stopping it and his blood tests returned to normal.
Methodology
Case report detailing the patient's symptoms, treatment, and recovery.
Limitations
The incidence of valproate induced hyperammonemic encephalopathy is not well established.
Participant Demographics
A 36-year-old man with a history of epilepsy and alcohol use.
Digital Object Identifier (DOI)
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