Liver Fluke Infection and Cholangiocarcinoma
Author Information
Author(s): Sripa Banchob, Kaewkes Sasithorn, Sithithaworn Paiboon, Mairiang Eimorn, Laha Thewarach, Smout Michael, Pairojkul Chawalit, Bhudhisawasdi Vajaraphongsa, Tesana Smarn, Thinkamrop Bandit, Bethony Jeffrey M, Loukas Alex, Brindley Paul J
Primary Institution: Khon Kaen University, Khon Kaen, Thailand
Hypothesis
The study investigates the link between liver fluke infection and the development of cholangiocarcinoma.
Conclusion
Liver fluke infection is strongly associated with an increased risk of cholangiocarcinoma, particularly in regions where the infection is endemic.
Supporting Evidence
- More than 600 million people are at risk of liver fluke infection.
- Heavy fluke infections are associated with various hepatobiliary diseases.
- Cholangiocarcinoma incidence is significantly higher in regions with prevalent liver fluke infections.
Takeaway
Eating raw fish can make you sick because it can carry tiny worms that can cause a type of cancer in your liver.
Limitations
The study primarily focuses on opisthorchiasis and may not fully address other factors contributing to cholangiocarcinoma.
Participant Demographics
The study discusses populations in Thailand, Laos, and other Southeast Asian countries.
Digital Object Identifier (DOI)
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