Erythema multiforme due to antitubercular drugs
2011
Erythema Multiforme Caused by Antitubercular Drugs
Sample size: 1
publication
Evidence: low
Author Information
Author(s): Gulati Sameer, Paljor H. P., Mahajan Rohit, Goel Pankaj
Primary Institution: St Stephen’s Hospital, Tis Hazari, Delhi, India
Hypothesis
Can antitubercular drugs cause erythema multiforme in patients?
Conclusion
The patient likely had erythema multiforme due to pyrazinamide, which was identified as the offending drug after reintroducing other antitubercular medications without issues.
Supporting Evidence
- The patient had maculopapular rashes after starting antitubercular therapy.
- Skin biopsy confirmed erythema multiforme.
- Discontinuation of all antitubercular drugs led to improvement of skin lesions.
Takeaway
A man developed a skin rash after starting tuberculosis treatment, and doctors figured out which medicine caused it by trying them again one at a time.
Methodology
The patient was treated conservatively, and antitubercular drugs were reintroduced one by one to identify the offending drug.
Participant Demographics
An 84-year-old male from Delhi, India.
Digital Object Identifier (DOI)
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