Possible New Hepatitis B Virus Genotype in Southeast Asia
Author Information
Author(s): Olinger Christophe M., Jutavijittum Prapan, Hübschen Judith M., Yousukh Amnat, Samountry Bounthome, Thammavong Te, Toriyama Kan, Muller Claude P.
Primary Institution: National Public Health Laboratory/Centre de Recherche Public–Santé, Luxembourg
Hypothesis
A new genotype of hepatitis B virus has emerged in Southeast Asia, specifically in Laos.
Conclusion
The study identifies a new hepatitis B virus genotype I with two subgenotypes, I1 and I2, which likely originated from recombinations outside Southeast Asia.
Supporting Evidence
- 19 hepatitis B virus strains were analyzed, revealing two new subgenotypes.
- 8.7% of the population in Laos is chronically infected with hepatitis B virus.
- Phylogenetic analysis showed that the new genotype I strains did not group with known genotypes A-H.
Takeaway
Scientists found a new type of hepatitis B virus in Laos that is different from the ones we already know about.
Methodology
Phylogenetic analysis of hepatitis B virus strains from blood donors in Laos.
Limitations
The study is based on a limited number of strains and may not represent the full diversity of hepatitis B virus in the region.
Participant Demographics
Blood donors from Vientiane City and central provinces of Laos.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website