Post-Kala-Azar Dermal Leishmaniasis in Mymensingh, Bangladesh
2011

Post-Kala-Azar Dermal Leishmaniasis in Bangladesh

publication Evidence: low

Author Information

Author(s): Islam Shamim, Ashraful Alam Bhuiyan, Caryn Bern

Primary Institution: Children's Hospital and Research Center Oakland

Hypothesis

What are the characteristics and implications of post-kala-azar dermal leishmaniasis (PKDL) in patients previously treated for kala-azar?

Conclusion

Post-kala-azar dermal leishmaniasis is a chronic skin condition that can occur in patients who have been treated for kala-azar, and it poses a risk of further transmission of the disease.

Supporting Evidence

  • Post-kala-azar dermal leishmaniasis (PKDL) is seen in patients who have been treated for kala-azar.
  • The incidence of PKDL in the Indian subcontinent is 5-10% after kala-azar treatment.
  • PKDL can be infectious to sand flies, contributing to the transmission of visceral leishmaniasis.

Takeaway

Some people who get treated for a disease called kala-azar can later develop a skin problem called PKDL, which can spread the disease to others.

Methodology

The study involved a case report of a patient with PKDL and a review of treatment regimens and incidence rates.

Limitations

The study is based on a single case report and may not represent the broader population.

Participant Demographics

A 50-year-old man from Mymensingh district, Bangladesh.

Digital Object Identifier (DOI)

10.4269/ajtmh.2011.11-0128

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