Alcohol and Smoking Effects on Oesophageal Cancer
Author Information
Author(s): Saeki H, Ohno S, Araki K, Egashira A, Kawaguchi H, Ikeda Y, Morita M, Kitamura K, Sugimachi K
Primary Institution: The Second Department of Surgery, Faculty of Medicine, Kyushu University
Hypothesis
Does heavy alcohol consumption and cigarette smoking increase p53 protein accumulation in oesophageal squamous cell carcinoma?
Conclusion
Heavy alcohol drinkers and cigarette smokers have a higher frequency of p53 protein accumulation in oesophageal squamous cell carcinoma.
Supporting Evidence
- A significantly larger proportion of heavy alcohol drinkers and cigarette smokers was evident in the p53-positive group.
- The combination of drinking and smoking was associated with a high frequency of p53 protein accumulation.
Takeaway
Drinking a lot of alcohol and smoking cigarettes can lead to more of a certain protein that is linked to a type of throat cancer.
Methodology
The study investigated p53 protein expression levels in patients with oesophageal squamous cell carcinoma.
Participant Demographics
Japanese patients with oesophageal squamous cell carcinoma.
Digital Object Identifier (DOI)
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