COLOMBOS: Access Port for Cross-Platform Bacterial Expression Compendia
Author Information
Author(s): Kristof Engelen, Qiang Fu, Pieter Meysman, Aminael Sánchez-RodrÃguez, Riet De Smet, Karen Lemmens, Ana Carolina Fierro, Kathleen Marchal
Primary Institution: Katholieke Universiteit Leuven
Hypothesis
The study aims to create comprehensive organism-specific cross-platform expression compendia for bacterial model organisms.
Conclusion
The COLOMBOS portal provides a unique resource for microbiologists to access and analyze expression data from multiple microarray platforms.
Supporting Evidence
- COLOMBOS integrates expression data from different microarray platforms.
- The compendia are extensively annotated for usability.
- COLOMBOS provides tools for exploring and visualizing expression data.
- The study illustrates the benefits of direct integration of expression values.
- COLOMBOS is unique in offering compendia for Bacillus subtilis and Salmonella enterica.
Takeaway
The researchers built a website called COLOMBOS that helps scientists look at gene expression data from different bacteria all in one place.
Methodology
The study involved constructing cross-platform expression compendia for three bacterial species and developing an access portal with analysis tools.
Limitations
The compendia may not cover all bacterial species and rely on the availability of public microarray data.
Digital Object Identifier (DOI)
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