Predictive Factors of Amputation in Diabetic Foot
Author Information
Author(s): Farine Francesco, Rapisarda Antonio Maria, Roani Carolina, Giuli Cristina, Comisi Chiara, Mascio Antonio, Greco Tommaso, Maccauro Giulio, Perisano Carlo
Primary Institution: Fondazione Policlinico Universitario A. Gemelli IRCCS
Hypothesis
Identifying risk factors related to surgical amputation treatment of diabetic foot can help provide alternatives to amputation.
Conclusion
Lower hemoglobin levels and elevated inflammatory markers are associated with a higher risk of lower-limb amputation in diabetic foot patients.
Supporting Evidence
- Lower hemoglobin levels were significantly correlated with the need for amputation.
- Elevated CRP, NLR, and PLR levels were associated with higher amputation risk.
- Older age was linked to a negative prognosis in diabetic foot patients.
- Patients evaluated within 5 days before surgery had lower hemoglobin and higher inflammatory markers.
Takeaway
If you have diabetes and a foot sore, doctors can check your blood to see if you might need an amputation. Lower blood counts can mean more risk.
Methodology
A retrospective case-control study analyzing laboratory data from 200 patients who underwent lower limb amputation for diabetic foot.
Potential Biases
Potential biases in case and control selection and retrospective data collection.
Limitations
The study's retrospective design limits causality determination and may introduce selection bias.
Participant Demographics
Patients older than 18 years who underwent lower extremity amputation due to diabetic foot complications.
Statistical Information
P-Value
0.001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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