Methods for Measuring Famotidine in Tablets
Author Information
Author(s): O. Zenita, K. Basavaiah
Primary Institution: Department of Chemistry, University of Mysore, Manasagangothri, Mysore 570 006, India
Hypothesis
The study aims to develop simple, sensitive, and cost-effective methods for the determination of famotidine in pharmaceutical formulations.
Conclusion
The developed methods are simple, accurate, and precise for determining famotidine in pure and tablet forms.
Supporting Evidence
- The methods offer advantages of simplicity, speed, accuracy, and precision without the need for costly equipment.
- The proposed methods have been validated for linearity, sensitivity, precision, accuracy, selectivity, and recovery.
- The methods are sensitive, simple, and use eco-friendly chemicals.
Takeaway
The researchers created easy ways to measure a medicine called famotidine in tablets, making it quicker and cheaper to check how much is in them.
Methodology
Two titrimetric methods and two spectrophotometric methods were developed using N-bromosuccinimide (NBS) to measure famotidine.
Limitations
The methods may not be applicable to all formulations and could be affected by the presence of other substances.
Digital Object Identifier (DOI)
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