Assessing Heart Function in Patients with CRT
Author Information
Author(s): Dawoud Fady, Schuleri Karl, Hansford Rozann, Evers Kristine, Horacek B Milan, Halperin Henry, Lardo Albert
Primary Institution: Johns Hopkins University
Hypothesis
Can mechanical and electrical activation be quantified in patients with CRT devices using CMR and EMI?
Conclusion
CMR and non-invasive EMI can effectively assess mechanical and electrical synchrony in patients with CRT devices.
Supporting Evidence
- CURE decreased from 0.73 to 0.51 when the device was turned off, indicating increased mechanical dyssynchrony.
- LVEF decreased from 42% to 29% when comparing pacing on and off.
- Electrical dyssynchrony was indicated without biventricular pacing, showing a negative ΔMTA of -26 ms.
Takeaway
This study looked at how well heart devices work by measuring heart activity in patients, showing that we can see how well the heart is synchronized.
Methodology
Patients with biventricular CRT were mapped with body surface electrodes and CMR tagging to analyze mechanical and electrical activation.
Limitations
Only 2 patients underwent full analysis, limiting the generalizability of the findings.
Participant Demographics
Patients with heart failure and left bundle branch block who had CRT devices for more than 9 months.
Digital Object Identifier (DOI)
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