Asthma Control with Different Inhalers
Author Information
Author(s): Veronika Müller, Gabriella Gálffy, Noemi Eszes, György Losonczy, Andrea Bizzi, Gabriele Nicolini, Henry Chrystyn, Lilla Tamási
Primary Institution: Semmelweis Medical University, Budapest, Hungary
Hypothesis
Does the type of inhaler affect asthma control in patients using fixed combinations of inhaled corticosteroids and long-acting beta-agonists?
Conclusion
Patients using the extrafine BDP/F pMDI had better asthma control compared to those using larger particle DPIs.
Supporting Evidence
- Asthma control was achieved by 45.9% of patients.
- Patients using extrafine BDP/F had significantly lower asthma control scores compared to those using DPI.
- The mean daily ICS dose was significantly lower in the extrafine pMDI group.
Takeaway
This study found that using a special inhaler helps people with asthma breathe better than using other types of inhalers.
Methodology
This was a cross-sectional study assessing asthma control and spirometry in outpatients with moderate to severe persistent asthma.
Potential Biases
The study included current or former smokers, which may influence asthma control outcomes.
Limitations
The study did not assess lung function parameters comprehensively, and the definition of asthma control differed from GINA guidelines.
Participant Demographics
111 patients (81 women, 30 men) aged 18 and older with moderate to severe persistent asthma.
Statistical Information
P-Value
p = 0.031
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website