Caudal regression syndrome and popliteal webbing in connection with maternal diabetes mellitus: a case report and literature review
2008
Caudal Regression Syndrome and Maternal Diabetes: A Case Report
Sample size: 1
publication
Evidence: low
Author Information
Author(s): Al Kaissi Ali, Klaushofer Klaus, Grill Franz
Primary Institution: Ludwig Boltzmann Institute of Osteology, Hanusch Hospital of WGKK and AUVA Trauma Centre Meidling, Vienna, Austria
Hypothesis
Is there a connection between maternal diabetes and the occurrence of caudal regression syndrome in offspring?
Conclusion
The study shows that children born to diabetic mothers are at a significant risk of developing caudal regression syndrome.
Supporting Evidence
- Infants of diabetic mothers have two to three times the average incidence of congenital anomalies.
- The patient demonstrated total sacral agenesis associated with subtotal lumbar agenesis.
- Careful diabetic control in the preconceptional period may lower the chances of congenital anomalies.
Takeaway
If a mom has diabetes, her baby might have problems with their spine and legs when they are born.
Methodology
Case report and literature review.
Participant Demographics
7-year-old boy from a non-consanguineous family in Austria.
Digital Object Identifier (DOI)
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