High Incidence of Vertebral Fracture in Women with Breast Cancer
Author Information
Author(s): Kanis J A, McCloskey E V, Powles T, Paterson A H G, Ashley S, Spector T
Primary Institution: WHO Collaborating Centre for Metabolic Bone Diseases, University of Sheffield Medical School
Hypothesis
Does breast cancer treatment increase the risk of vertebral fractures in women?
Conclusion
Women with breast cancer have a significantly higher risk of vertebral fractures compared to the general population.
Supporting Evidence
- The incidence of vertebral fracture was nearly five times greater than normal in women from the time of first diagnosis.
- The odds ratio for vertebral fractures in women with soft-tissue metastases was 22.7.
Takeaway
Women with breast cancer are much more likely to have broken bones in their spine than women without breast cancer.
Methodology
The study compared vertebral fracture prevalence in women with non-metastatic breast cancer to an age-matched general population sample.
Participant Demographics
Women with non-metastatic breast cancer.
Statistical Information
Confidence Interval
95% CI, 2.3–9.9
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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