Therapeutic Effects of Taurine and Histidine Supplementation in Retinal Diseases
Author Information
Author(s): Lee Deokho, Smith Lois E. H., Hu Zhihong Jewel
Primary Institution: Department of Ophthalmology, Boston Children’s Hospital, Harvard Medical School
Hypothesis
Can taurine and histidine supplementation protect against retinal diseases?
Conclusion
Taurine and histidine supplementation may provide neuroprotective effects and reduce retinal damage in various eye diseases.
Supporting Evidence
- Taurine supplementation has shown protective effects against retinal ganglion cell damage in various animal models.
- Histidine supplementation may reduce retinal neovascularization in oxygen-induced retinopathy models.
- Both taurine and histidine have potential roles in managing oxidative stress in retinal diseases.
Takeaway
This study suggests that giving certain amino acids like taurine and histidine can help protect our eyes from diseases.
Methodology
The review summarizes preclinical evidence on the effects of taurine and histidine supplementation in retinal diseases.
Limitations
The review highlights the lack of robust clinical studies on amino acid supplementation in retinopathy.
Digital Object Identifier (DOI)
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