A phylogenomic profile of hemerythrins, the nonheme diiron binding respiratory proteins
2008

Study of Hemerythrins in Different Organisms

publication Evidence: moderate

Author Information

Author(s): Bailly Xavier, Vanin Stefano, Chabasse Christine, Mizuguchi Kenji, Vinogradov Serge N

Hypothesis

What is the phylogenomic profile and function of hemerythrins across various organisms?

Conclusion

Hemerythrins are limited in occurrence among bacteria and archaea and are largely absent in multicellular organisms, suggesting a loss of the Hr gene in deuterostome ancestors.

Supporting Evidence

  • Hemerythrins are found in a limited number of bacteria and archaea.
  • The study identified hemerythrins in several eukaryotic groups, including some metazoans.
  • The presence of hemerythrins suggests they may have evolved to serve specific functions in oxygen transport.

Takeaway

Hemerythrins are special proteins that help some animals transport oxygen, but they are not very common in most living things.

Methodology

The study involved searching for hemerythrin sequences in the genomes of various archaea, bacteria, and eukaryotes, along with phylogenetic analysis.

Limitations

The study's findings are based on the limited occurrence of hemerythrins in the sampled genomes, which may not represent all organisms.

Digital Object Identifier (DOI)

10.1186/1471-2148-8-244

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