Energy Use and Body Temperature in Tumor-Bearing Rats
Author Information
Author(s): Oudart H, Malan A, Maho Y le, Geloen A
Primary Institution: Centre d’Ecologie et Physiologie Energétiques, associé à l’Université Louis Pasteur
Hypothesis
The study investigates the energy metabolism and body temperature in cachectic rats bearing the Yoshida sarcoma compared to control rats.
Conclusion
The study found that tumor-bearing rats had higher resting energy expenditure during the day but similar total energy expenditure compared to control rats.
Supporting Evidence
- Resting energy expenditure was higher in tumor-bearing rats than in control groups.
- Total energy expenditure did not differ between tumor-bearing and ad-libitum fed rats.
- Energy expenditure was higher in tumor-bearing rats during the day compared to control rats.
Takeaway
Rats with tumors use more energy during the day but not at night, and they also have a fever during the day.
Methodology
The study used indirect calorimetry to measure energy expenditure and monitored body temperature in different groups of rats.
Participant Demographics
The study involved anorectic and cachectic rats bearing the Yoshida sarcoma, compared to pair-fed and ad-libitum fed control rats.
Digital Object Identifier (DOI)
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